2025.11.03 05:23

Molecular Pharmaceutics

修士課程修了生の鈴木君を中心に、薬学科卒業生の坂本君、山内さん、橋本さん、中口さん、坂井さん、薬科学専攻博士1年の石鍋君が携わった、慶應義塾大学医学部、金沢大学、京都大学との共同研究論文が掲載されました。

Rat-Specific Expression of Placental MATE1 Contributes to Species Difference in Fetal Transfer of Me

Metformin readily crosses the human placenta. However, the fetal-to-maternal plasma concentration ratio (F/M ratio) of metformin has been reported to be as low as 0.057 in rats. This study investigated the underlying mechanisms of these interspecies differences by examining the expression and functi …

PubMed

慶應義塾大学薬学部薬剤学講座

Division of Pharmaceutics, Keio University Faculty of Pharmacy