2023.11.29 05:00

Journal of Pharmaceutical Sciences

西村准教授を中心に、薬学科卒業生の石井まりさんが携わった、三重大学医学部との共同研究論文が掲載されました。

Breast cancer resistance protein limits fetal transfer of tadalafil in mice: BCRP limits fetal trans

Tadalafil, a phosphodiesterase 5 (PDE5) inhibitor, is a candidate therapeutic agent for fetal growth restriction and hypertensive disorders of pregnancy. In this study, we elucidated the fetal transfer of tadalafil in comparison with that of sildenafil, the first PDE5 inhibitor to be approved. We al …

PubMed

慶應義塾大学薬学部薬剤学講座

Division of Pharmaceutics, Keio University Faculty of Pharmacy